Synonyms: (17beta)-Estra-1,3,5(10)-triene-3,17-diol 3-benzoate;1,3,5(10)-Estratriene-3,17-diol-3-benzoate;1,3,5(10)-Oestratriene-3,17-beta-diol 3-benzoate;1,3,5(10)-oestratriene-3,17-beta-diol3-benzoate;17beta-Estradiol monobenzoate;17-beta-estradiolmonobenzoate;17-beta-Oestradiol 3-benzoate;17-beta-oestradiol3-benzoate
Chemical Properties White solid
Usage antiacne, antineoplastic
Usage Estradiol is the major estrogen secreted by the premenopausal ovary. Estradiol benzoate is an estradiol analog which contains a benzyl ester at the C-3 position. Estradiol benzoate is useful in the tr eatment of lesions produced by diminution of bodily production of estrogens.
Estrogens direct the development of the female genotype in embryogenesis and at puberty. Estradiol is the major estrogen secreted by the premenopausal ovary. Estradiol benzoate is an estradiol analog which contains a benzyl ester at the C-3 position and is often used in combination with a progestin to induce estrus in domestic livestock. This compound binds to the human and murine estrogen receptor α (ERα), and chicken ER with IC50 values in the range of 22-28 nM. This reflects a 6-10 fold reduction in binding affinity compared to estradiol.
The effects of daily injections of 5 microgram estradiol benzoate (EB) on the patterns of food and ethanol consumption were studied in ovarectomized rats given free access to food, a 10% ethanol solution, and water. EB led to an immediate, but transient, suppression of both food and ethanol intake. The time course and magnitude of these effects were virtually identical. While the decrease in total food intake was achieved by a permanent decrease in the duration of eating bouts, the decline in total ethanol consumption apparently resulted from decreased rates of licking within bouts. Gradual increases in the frequency of eating and ethanol-drinking bouts allowed total food and ethanol intake to return to baseline within three weeks of the first injection. Total water intake rose three-fold during EB administration and this was due to increases in both the duration and frequency of drinking bouts. The similarity in effects induced by EB on the patterns of food and ethanol intake were discussed in terms of ethanols caloric property.
|ANALYTICAL ITEMS||SPECIFICATION||ANALYTICAL RESULTS|
|Melting point||191-198 °C(lit.)||Confirms|
|Loss on drying||≤0.1%||0.02%|
|Conclusion||The specification conform with Enterprise Standard|
Related Products you may need:
|Estradiol valerate||Estriol||Hydrocortisone acetate|
|Estradiol benzoate||Nylestriol||Betamethasone 17-valerate|
|Estradiol cypionate||Diethylstilbestrol||Prednisone acetate|
|Algestone acetophenide||Medroxyprogesterone acetate||Clobetasol propionate|
|Lynestrenol||Allylestrenol||Prednisolone phosphate sodium|
|Chlormadinone acetate||Dienogestrel||Fluorometholone Acetate|
|Cyproterone acetate||Drospirenone||Dexamethasone Acetate|
|Megestrol acetate||Pregnenolone||Dexamethasone Sodium Phosphate|
(1) High Quality:Kafen Biotech is a steroids manufacturer with its own lab and factory.
The purity of our product is tested by our quality department before it is shipped to our clients. Mostly steroids are 99% purity and approved by SGS,CTI and ITS.
(2) Favorable Price: Our price meets international market performance and we give the best doiscounted price for our new customers and promotioned price for our regular customers.
(3) Safe Fast Delivery: After receiving your payment,we will have professional package team to arrange your parcel within 12 hours.We can guarantee every goods can be successfully deliveried.
(4) Available Shipment Way: EMS,HongKong Post,DHL,TNT,UPS,FedEx,Registered Mail,Air Express,Sea Vessel etc.
(5) After-Sale Service: We can offer you good service after you place an order.At the same time,we can offer you some homebrew recipe to make injection.More service is more available to you.
1. Competitive prices: For small order and bulk purchase, the price will be different. A good discount would be given when you make a large order, we usually send extra powders as gift to our customers.
2. Top quality: With our years of experience, advanced technology and continuous research, our quality is to fully meet the needs of the market and the requirements of customers. All of our products are highly quality guaranteed, once any problem is found, the package would be reshipped for you.
3. Discreet package: All orders are packed the way suits you best to cross customs safely. Since this is related to size and value of your order, it may come in more than one package. Or if you have your own ideal way, it could be also taken into consideration.
4. Security Shipping: Wed like to send by different express(EMS,TNT,DHL,FedEx) at one period of time. The most professional forwarder would be recommanded for you.
5. Fast delivery: We have stock, so we can delivery quickly once payment is received.
6. Rich experience: Our company is a professional production leading factory in China in pharmaceutical area of many years, our products have exported to Germany, Spain, UK, USA, Australia, Middle East and so many other countries, and we have got very good feedback from our customers, we had established long friendly relations of cooperation.
7. Best service: We will give you warm after-sale service, any of your question would be solved as soon as possible.
Estradiol Benzoate Pharmaceutical Raw Materials CAS 50-50-0 Female Sex Images